| noun | an effortful attempt to attain a goal |
| noun | a symptom of some physical hurt or disorder “the patient developed severe pain and distension” |
| noun | emotional distress; a fundamental feeling that people try to avoid “the pain of loneliness” |
| noun | a somatic sensation of acute discomfort “as the intensity increased the sensation changed from tickle to pain” |
| noun | a bothersome annoying person “that kid is a terrible pain” |
| noun | something or someone that causes trouble; a source of unhappiness “washing dishes was a nuisance before we got a dish washer” |
| verb | cause bodily suffering to and make sick or indisposed |
| verb | cause emotional anguish or make miserable “It pains me to see my children not being taught well in school” |
| strive | verb | attempt by employing effort |
| strenuous | adjective | taxing to the utmost; testing powers of endurance; ; ; - F.D.Roosevelt |
| strain | verb | use to the utmost; exert vigorously or to full capacity |
| pain | verb | cause emotional anguish or make miserable |
| hurt | verb | feel physical pain |
| painful | adjective | causing misery or pain or distress |
| bother | verb | cause annoyance in; disturb, especially by minor irritations |
| trouble | noun | an event causing distress or pain |
| ailment | noun | an often persistent bodily disorder or disease; a cause for complaining |
| pain | noun | a somatic sensation of acute discomfort |
| anguish | noun | extreme distress of body or mind |
| hurt | noun | feelings of mental or physical pain |