| verb | cause annoyance in; disturb, especially by minor irritations “Mosquitoes buzzing in my ear really bothers me” |
| verb | excite to an abnormal condition, or chafe or inflame “Aspirin irritates my stomach” |
| verb | excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus “irritate the glands of a leaf” |
| adjective | causing irritation or annoyance “tapping an annoying rhythm on his glass with his fork” |
| adjective | (used of physical stimuli) serving to stimulate or excite “an irritative agent” |
| adjective | causing physical discomfort “bites of black flies are more than irritating; they can be very painful” |
| annoyer | noun | someone given to teasing (as by mocking or stirring curiosity) |
| annoyance | noun | the act of troubling or annoying someone |
| botheration | noun | the psychological state of being irritated or annoyed |
| bother | noun | something or someone that causes trouble; a source of unhappiness |
| irritation | noun | the psychological state of being irritated or annoyed |
| irritant | noun | something that causes irritation and annoyance |
| vexation | noun | the psychological state of being irritated or annoyed |
| vexer | noun | someone given to teasing (as by mocking or stirring curiosity) |
| devilment | noun | reckless or malicious behavior that causes discomfort or annoyance in others |
| deviltry | noun | reckless or malicious behavior that causes discomfort or annoyance in others |
| devilry | noun | reckless or malicious behavior that causes discomfort or annoyance in others |
| irritative | adjective | (used of physical stimuli) serving to stimulate or excite |
| plague | noun | an annoyance |
| irritate | verb | excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus |
| painfulness | noun | the quality of being painful |